- St Athanasius manfully defended the deity of Christ
- St Basil, St Gregory Nazianzus, St John Chrysostom and St Hilary defended the dogma of the Holy Trinity
- St Basil, in particular, defended the deity of the Holy Spirit
- St Jerome manfully defended the perpetual virginity of our Lady
- St Cyril manfully defended Mary as "Mother of God"
- St Leo manfully defended the humanity of Christ and the hypostatic union of the two natures of Christ
- St John Damascene manfully defended the images of Christ, Mary, and the Saints
- John Duns Scotus manfully defended the doctrine of Mary's Immaculate Conception
Note: All are both saints and Doctors of the Church except John Duns Scotus. Taylor Marshall has a great post on this. John Duns Scouts - Our Next Saint and Doctor of the Church