Hundreds of thousands of Christians have been displaced from their homes and countless others have been murdered or enslaved by the jihadist army, with no end in sight.
Sister Hatune Dogan has been on the ground and witnessed the devastation of these ancient Christian communities. She's listened to survivors tell how Christians and Yazidi women are being sold into sex slavery.
"They choose the most beautiful one, even if they have a small child, and they sell these women, these ladies to each other. They don't sell to another religion -- only Sunni Muslim," Dogan said.
Her foundation helps the poor and persecuted in 35 countries, providing them with food, clothing, medicine and shelter.
Sister Dogan is no stranger to Islamic persecution. As a young girl, threats from local Muslims forced her family to leave their home in Turkey.
"The mission of (Abu Bakr) Baghdadi, of ISIS, is to convert the world completely to the Islamic religion and bring them to Dar Al Salaam, as they call it. And Islam is not peace, please. Whoever says ISIS has no connection to Islam or something like this is, he's a liar. ISIS is Islam; Islam is ISIS," Dogan explained.
She's disappointed by what she calls a weak reaction from the West.